%0 Journal Article %T Change in the Resistance of Pseudomonas Aeruginosa Strains Which Were Isolated, Over the Years %A Oktay YAPICI %J - %D 2018 %X Pseudomonas aeruginosa is one of the most commonly encountered factors of nosocomial infections with high mortality and morbidity rates. In addition to its adverse effects, prognosis increases the length of hospital stay and cost as well. It is important to know the resistance as part of the empiric treatment approach to nosocomial infections. This study aimed to analyze the resistance of P. aeruginosa strains against the antibiotics over the years by using the clinical samples obtained from the microbiology laboratory, and to determine the proper policies for empirical antibiotic use. Antibiotic susceptibility of 626 P. aeruginosa strains which were isolated between 2013 and 2016 was evaluated retrospectively. Conventional and automated identification systems were used to identify the isolated factors. Antibiotic susceptibility of the isolates were specified through VITEK 2 automated system based on the criteria of Clinical and Laboratory Standards Institute (CLSI). 91, 132 and 340 of 626 isolates were isolated from hemoculture, urine and airway, respectively. The remaining strains were isolated from the other samples. The lowest resistance rate belonged to the resistance against cholistin and no change was observed within years in this respect. The highest rate of resistance was determined in piperasilin (%61.79) in 2016 and when compered to the rate of 2013, it was found significant high statically (p=0.01). Updated data should be taken into consideration as the empirical antibiotic treatment is initiated for P. aeruginosa strains that can cause nosocomial infections, because susceptibility patterns of the strains may vary depending on the hospital, years as well %K Antibiyotik Duyarl£¿l£¿£¿£¿ %K Hastane Enfeksiyonlar£¿ %K Pseudomonas Aeruginosa %U http://dergipark.org.tr/muskutd/issue/38576/447593