%0 Journal Article
%T Effect of Fat Graft on Temporomandibular Joint Disc Disorders
%A Ay£¿e KALAY
%J -
%D 2018
%X Temporomandibular joint (TMJ) is the growth center of the mandible and has a critical importance for functions such as chewing, breathing and speech. Osteoarthritis is the most common type of arthritis of the TMJ.It is difficult to treat cartilage damage due to the poor blood supply of the cartilage tissue and the low potential for healing.In this study,we investigated the effects of fat graft,which has the potential of transforming into many cells and has many growth factors,on damaged temporomandibular articular cartilage. In this study,joint degeneration model was created by creating 3 mm defects in both TMJ disc laterals of subjects.A fat graft from the inguinal region was placed on the left side and the right side was closed as a control group without further treatment. Histopathological evaluation of joint surface structure,chondrocyte density,cell clustering and Safranin O staining loss parameters were scored by a single expert histologist in both groups. As a result,it was seen that the deterioration of joint surface structure was statistically significantly lower in the experimental group.Although the cluster score was low in the experimental group,no statistically significant difference was found.Chondrocyte density and safranin O staining showed similar values between the two groups
%K ya£¿ grefti
%K temporomandibular eklem
%K osteoartrit
%U http://dergipark.org.tr/uutfd/issue/40996/419856