%0 Journal Article
%T Comparison of three different creatinine clearance calculation methods in patients with type 2 diabetes mellitus
%A Fatih Orkun Kundaktepe
%J -
%D 2018
%X Aim: To determine the most accurate and useful method for calculating creatinine clearance by comparing the results of different methods. Methods: One hundred type 2 diabetic patients who have been followed by Okmeydani Training and Research Hospital Internal Medicine and/or diabetes outpatient clinics were included in this study. Individuals with hypertension, acute kidney disease and renal transplantation were excluded from the study. Results: Glomerular filtration rate (GFR) calculated with Cockcroft-Gault formula was significantly affected by creatinine, weight, and age (p<0.050 for all). GFR measured with Modification of Diet in Renal Disease (MDRD) formula was significantly affected by creatinine and age (p<0.050 for all) in a univariate model; in a multivariate model, this was significantly independently affected by creatinine (p=0.001). GFR measured with 24h urine was significantly affected by creatinine, weight, and age (p<0.050 for all) in a univariate model; in a multivariate model, this was significantly independently affected by weight (p=0.001). Conclusion: In this study, those three methods revealed similar results. All of three methods can be used for evaluating renal functions in Type II diabetic patients but creatinine clearance with 24 hours urine method requires two patient visits in a row and a more complex biochemistry laboratory; so in our opinion, this method may be used as an alternative to the other two methods
%K Kreatinin klirensi
%K glomeruler filtrasyon h£¿z£¿
%K tip 2 diyabet
%U http://dergipark.org.tr/acem/issue/39803/434689