%0 Journal Article
%T The Impact of 17弛 Estradiol Level Variations on Blood Lymphocyte Counts Among Healthy Females
%A Gˋkˋen ˋrg邦l
%J -
%D 2018
%X Objective: To investigate the effects of 17汕-estradiol (E2) levels on blood lymphocyte counts in women. Methods: Blood samples were obtained from 428 healthy women. Serum E2 levels were measured using the solid-phase enzyme-labelled chemiluminescent method. Complete blood count was performed by a fully automated cell counter. White blood cell differential, including lymphocytes, was performed by volume, conductivity, and five-part scatter measurements (VCS technology). The participants were divided into four groups, according to the blood lymphocyte levels: <1000 cells/米L (Group A), 1001每2000 cells/米L (Group B), 2001每3000 cells/米L (Group C), and 3001每4000 cells/米L (Group D). Results: The mean age of the participants was 37.03 years (between 15 and 66 years). E2 levels on admission in the study group ranged from <11 to 4264 pg/mL, and the median E2 level was 121.98. Twelve women had high levels of E2, as a result of the ovulation induction treatment. Total lymphocyte count varied between 0.9℅103 to as high as 105℅103 cells/米L, and the median lymphocyte count was 2.6℅103 cells/米L. Lymphocyte每white blood cell ratio (LWR) was also studied in addition to lymphocyte levels. The lowest LWR value was 9.1 and the highest was 99.7. The medium E2 concentration was 40.3㊣11, 114㊣144, 117.2㊣128, and 192.2㊣595 in Groups A每D, respectively. The relationship between lymphocyte counts and LWR was positive, as expected. There were no statistically significant differences in lymphocyte counts either with age or E2 levels. Conclusion: It is well established that estrogens affect lymphocyte functions in several ways. In the present study, we were unable to demonstrate a correlation between the E2 serum levels and blood lymphocyte counts in women
%K 17 汕 estradiol
%K lenfosit
%K beyaz kan h邦creleri
%U http://dergipark.org.tr/marusbed/issue/39370/464599