%0 Journal Article
%T Efficacy of Noninvasive King, Bonacini, FibroQ Tests in Determining Fibrosis in Chronic Hepatitis B Infection
%A Kadri ATAY
%J -
%D 2019
%X Background : Liver biopsy is recommended before antiviral treatment for patients with chronic hepatitis B. Although liver biopsy is the gold standard procedure, many noninvasive tests have been established for the determining of liver damage. The objective of this study was to compare the performances of several noninvasive indirect biochemical markers used to detect advanced fibrosis in patients with chronic hepatitis B. Methods : In total, 91 patients with chronic hepatitis B were included .Then patient with chronic hepatitis B infection were divided as a mild and advanced fibrosis and this two groups were compared Results: The mean age was 39.5 ¡À 14.9.The areas under receiver operating characteristic curve in the prediction of significant fibrosis were 0.756, 0.849, 0.742 and 0.825 for King score, Bonacini (CDS index), FibroQ score. FibroQ and King score were the best indicators for the detection of advanced fibrosis. For FIB 4 and AP index , the cut-off value for the prediction of advanced fibrosis were ¡Ư 1,55 and ¡Ư9,7 with a sensitivity and specificity of 82% ,91% and 70%,67% respectively. ( p<0.0001) Conclusions: According to the results of our study, FibroQ score and King score may be considered as a good indicator for predicting advanced fibrosis in chronic hepatitis B subject
%K Kronik hepatit B
%K Karaci£¿er biyopsi
%K Fibrozis
%U http://dergipark.org.tr/hutfd/issue/44085/525258