%0 Journal Article
%T A RESEARCH FOR SOME OXAZOLIDINONES TO EVALUATE THEIR ANTIMICROBIAL ACTIVITY
%A Canan KUS
%J -
%D 2018
%X Objectives: In this research, antimicrobial activity of some new oxazolidinone derivatives were evaluated against S. aureus ATCC 25923, E. coli ATCC 25922, B. subtilis ATCC 6633, methicillin-resistant Staphylococcus aureus (MRSA) clinical isolate and C. albicans ATCC 10231. Material and Method: Formerly obtained and published 10 oxazolidinones were tested against antimicrobial activity and this evaluation was carried out in Mueller-Hinton broth and Sabouraud dextrose broth. Result and Discussion: Compounds E5, and E9 showed antimicrobial activity against both bacteria and fungi with 25 ¦Ìg/mL and 50 ¦Ìg/mL, respectively. Our present research and the others have shown that the electro-negativity degree is very important for the biological activity
%K antimikrobiyal aktivite
%K linezolid
%K oksazolidinon
%U http://dergipark.org.tr/jfpanu/issue/42673/514572