%0 Journal Article
%T SPECIFIC BEHAVIOUR OF THE BLOOD SEDIMENTATION PROCESSES EXAMINED BY THE ELECTROCHEMICAL IMPEDANCE MICROSENSOR
%A Daniel Donoval
%A So¨¾a Flickyngerov¨¢
%A Vladim¨ªr Tvaro£¿ek
%A £¿tefan Durd¨ªk
%J -
%D 2013
%X Electrochemical impedance microsensor for the fast monitoring of the blood sedimentation has been developed. Planar microsensor consisted of the interdigital array of electrodes (IDAE - finger/gap widths of different values from 5/5 ¦Ìm to 400/400 ¦Ìm) based on Au or Pt thin films sputtered on Si/SiO2 or ceramic alumina substrates. IDAE microsensor allows time measurements of electrical impedance changes - impedance rates - (at frequencies of order 0.1 kHz and 10 kHz) of small blood drop applied on it. The determination of the impedance rate during sedimentation and the impedance spectrometry at a low-frequency range of order of 1 kHz seems to be very helpful for a quick diagnostics of the health state. In the IDAE microsensor erythrocyte aggregation/rapid settling/packing periods associated with dryperiod are overlapping due to the planar arrangement of dimensions in order of 1-100 ¦Ìm. The time monitoring of the blood sedimentation (in the range of 10-900 seconds) by the impedance method can distinguish between healthy and cancer state of blood and could serve for the simple long-term diagnostics after the surgical operation or as a screening procedure for early diagnoses
%K planar IDAE impedance microsensor
%K blood sedimentation
%U https://ojs.cvut.cz/ojs/index.php/CTJ/article/view/4297