%0 Journal Article %T Modeling of Circadian Rhythm under influence of Pain: an approach based on Multi-agent Simulation %A Adriano DE CEZARO %A Ang¨¦lica Theis DOS SANTOS %A Catia Maria dos Santos MACHADO %A Diana Francisca ADAMATTI %A Stefania DA SILVEIRA GLAESER %J - %D 2018 %R http://dx.doi.org/10.14201/ADCAIJ2018721725 %X The human body has endogenous biological rhythms. One of those rhythms is the circadian rhythm, with a cycle of approximate 24 hours, that is responsible for regulating many important functions of human body. In this contribution, we propose a nonlinear coupled differential equation for modelling some agents responsible for the circadian rhythm under the influence of pain. We show results concerning the well-posedness of a solution as well as an analysis on the synchronization for each agents. We use a multi-agent simulation strategy of an corresponding model as an alternative interpretation of the pain influences in the behavior of the circadian rhythm %K Multi-agent %K Circadian Rhythm %K Pain %U http://campus.usal.es/~revistas_trabajo/index.php/2255-2863/article/view/ADCAIJ2018721725