%0 Journal Article
%T A Laser Driven Flow Chemistry Platform for Scaling Photochemical Reactions with Visible Light
%J -
%D 2019
%R https://doi.org/10.1021/acscentsci.8b00728
%X High Resolution Image Download MS PowerPoint Slide Visible-light-promoted organic reactions can offer increased reactivity and selectivity via unique reaction pathways to address a multitude of practical synthetic problems, yet few practical solutions exist to employ these reactions for multikilogram production. We have developed a simple and versatile continuous stirred tank reactor (CSTR) equipped with a high-intensity laser to drive photochemical reactions at unprecedented rates in continuous flow, achieving kg/day throughput using a 100 mL reactor. Our approach to flow reactor design uses the Beer¨CLambert law as a guideline to optimize catalyst concentration and reactor depth for maximum throughput. This laser CSTR platform coupled with the rationale for design can be applied to a breadth of photochemical reactions
%U https://pubs.acs.org/doi/10.1021/acscentsci.8b00728