%0 Journal Article
%T Identification of a Strigoterpenoid with Dual Nrf2 and Nf-¦ÊB Modulatory Activity
%J -
%D 2019
%R https://doi.org/10.1021/acsmedchemlett.8b00604
%X The sesquiterpene¨Ccoumarin ether samarcandone provided a suitable framework to replace the apocarotenoid A¨CC ring system of strigol (1), replicating, after linking to a butenolide moiety, the activity of the natural phytohormone on Nrf2 and also showing potent NF-kB inhibitory activity, overall modulating two critical pathways of inflammation and cancer
%U https://pubs.acs.org/doi/10.1021/acsmedchemlett.8b00604