%0 Journal Article
%T Intermediate Water on Calcium Phosphate Minerals: Its Origin and Role in Crystal Growth
%J -
%D 2019
%R https://doi.org/10.1021/acsabm.9b00014
%X Water molecules are known to play crucial roles both in the formation and biological function of materials. Herein, we show the presence of ˇ°intermediate waterˇ± on an inorganic solid material, hydroxyapatite. In vitro experiments revealed that Mg substitution of apatite significantly enriched the amount of intermediate water, possibly due to the proton transfer to a hydrogen-bonded network of water around HPO42¨C on divalent-cation-deficient apatite surfaces. The intermediate water formation related to a markedly suppressed protein adsorption on apatite. Analysis of bone apatites suggested that the intermediate water on minerals could play crucial roles in regulating crystal growth
%U https://pubs.acs.org/doi/10.1021/acsabm.9b00014