%0 Journal Article
%T Boronic Acid Catalyzed Regioselective Aminolysis of 3,4-Epoxy Alcohols
%J -
%D 2018
%R https://doi.org/10.1021/acscatal.8b02591
%X A C-3 aminolysis of epoxy homoallylic alcohols has been accomplished, which was catalyzed by a commercially available boronic acid. Due to the directing effect of the hydroxyl moiety, the ring opening reaction of a variety of 3,4-epoxy alcohols bearing different substitution patterns with various aromatic amines as nucleophiles proceeded in a stereospecific reaction pathway at the C-3 position furnishing various amino alcohols as products in a highly regioselective manner
%U https://pubs.acs.org/doi/10.1021/acscatal.8b02591