%0 Journal Article
%T Supramolecular Threading of Peptide Hydrogel Fibrils
%J -
%D 2018
%R https://doi.org/10.1021/acsbiomaterials.8b00283
%X There is an increasing demand for biocompatible materials in biomedical applications. Herein, we report a modified ¦Á-helical decapeptide segment from the cardiac troponin C, which self-assembles into fibers with a secondary ¦Â-sheet structure. These fibers cross-link via a novel supramolecular threading mechanism which results in an atypical stiff hydrogel (G¡ä ¡Ö 13 kPa). In this work, we provide a first insight into the understanding of such remarkable cross-linking mechanism, which will aid in the development of new biomaterials with unique properties
%U https://pubs.acs.org/doi/10.1021/acsbiomaterials.8b00283