%0 Journal Article
%T Photoactive Oligo(p-phenylenevinylene) Functionalized with Phospholipid Units for Control and Visualization of Delivery into Living Cells
%J -
%D 2018
%R https://doi.org/10.1021/acsami.8b07847
%X To take advantage of the excellent optical properties of conjugated polymers (CPs) or conjugated oligomers (COs) for biological applications, there is still a requirement to find new ways to deliver these conjugated molecular materials into cells in a facile, controllable, and noninvasive manner. Herein, a photoactive oligo(p-phenylenevinylene) (OPV) derivative was covalently attached with phospholipid units (OPV¨Clipid) to enhance its dispersion in water and facilitate its internalization by cells. OPV¨Clipid could be delivered into either the cell membrane or cytoplasm controllably through the assistance of liposomes with different formulas. It could also act as a fluorescent probe for cell imaging and visualization of the delivery process. This work shows a good potential for delivering functional conjugated molecular materials into cells in a controllable way
%U https://pubs.acs.org/doi/10.1021/acsami.8b07847