%0 Journal Article %T Nanomaterials and Oxidative Stress %A Donald H. Atha %A Vytas Reipa %J - %D 2018 %R https://doi.org/10.3390/challe9010017 %X Abstract With the rapid development of new nanomaterials, it was recognized early that together with their beneficial properties, nanomaterials may pose a risk to human health and the environment. Evidence has accumulated over the last twenty years in support of oxidative stress as a broad mechanistic concept to explain the interaction of engineered nanoparticles with biological substances. As oxidative stress as a physiological response was recognized in redox biology, its wide-ranging use in nanotoxicology has exposed new challenges and limitations. In this commentary, we review certain oxidative stress concepts and their relevance to nanotoxicology. View Full-Tex %K oxidative stress %K redox potential %K nanotoxicology %K measurement %K nanoparticles %U https://www.mdpi.com/2078-1547/9/1/17