%0 Journal Article %T The Anti-Inflammatory Activity of Nigella sativa Balm Sticks %A Kori Yati %A Lusi Putri Dwita %A Sri Nevi Gantini %J - %D 2019 %R https://doi.org/10.3390/scipharm87010003 %X Abstract Nigella sativa oil has been known to have potent anti-inflammatory activity. This research aimed to determine the anti-inflammation activity of Nigella sativa oil in a simple balm stick by topical application. The activity was checked using two methods: carrageenan-induced paw oedema and granuloma pouch on rats. The results showed that balm sticks which contained 10% Nigella sativa could overcome both acute and sub-acute inflammation showing by high oedema inhibition (60.64%), low leucocytes count (43.55% lower than control) as well as a notable TNF-¦Á concentration (50% lower than control) on the inflamed area. In conclusion, topical application of a Nigella sativa balm stick was effective for both acute and sub-acute forms of inflammation. View Full-Tex %K Nigella sativa %K anti-inflammatory %K balm %K topical %U https://www.mdpi.com/2218-0532/87/1/3