%0 Journal Article
%T Schistosoma and Other Relevant Helminth Infections in HIV-Positive Individuals¡ªAn Overview
%A Amrei von Braun
%A Christoph L¨¹bbert
%A Henning Trawinski
%A Sebastian Wendt
%J -
%D 2019
%R https://doi.org/10.3390/tropicalmed4020065
%X Abstract For many years, researchers have postulated that helminthic infections may increase susceptibility to HIV, and that immune activation may have contributed to the extensive spread of HIV in sub-Saharan Africa. In the meantime, immunological studies have provided some evidence in support of this hypothesis, while cross-sectional clinical studies were able to further support the assumed association between HIV infection and selected helminthic co-infections. However, as many of the helminthic infections relevant to HIV-infected patients belong to the group of ¡°neglected tropical diseases¡±, as defined by the World Health Organization, a certain lack of attention has inhibited progress in fully scaling up treatment and prevention efforts. In addition, despite the fact that the challenges of co-infections have preoccupied clinicians for over two decades, relevant research questions remain unanswered. The following review aims to provide a concise overview of associations between HIV and selected helminthic co-infections concerning aspects of HIV acquisition and transmission, clinical and immunological findings in co-infected individuals, as well as treatment and prevention efforts. View Full-Tex
%K HIV
%K helminths
%K schistosomiasis
%K neglected tropical diseases
%U https://www.mdpi.com/2414-6366/4/2/65