%0 Journal Article
%T De Novo PITX1 Expression Controls Bi-Stable Transcriptional Circuits to Govern Self-Renewal and Differentiation in Squamous Cell Carcinoma
%J -
%D 2019
%R https://doi.org/10.1016/j.stem.2019.01.003
%X £¿ De novo Pitx1 expression defines tumor-propagating SCC cells £¿ PITX1 governs a feed-forward circuit that enables TPC-renewal and clonal expansion £¿ PITX1 function represses KLF4-dependent squamous differentiation £¿ Pitx1 expression and function are restricted by KLF4 activit
%U https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(19)30003-7