%0 Journal Article %T Exploring the Interneuron Canopy Atop the ¡®Impenetrable Jungle¡¯ %J - %D 2019 %R https://doi.org/10.1016/j.tins.2019.01.001 %X The multifaceted functions of the brain are borne through seemingly infinite spatiotemporal interactions between its resident neural elements. Using a combinatorial approach, Schuman and colleagues ( J. Neurosci. 2018;39:125¨C139) recently identify four layer 1 cortical interneuron subtypes, including a hitherto uncharacterized neuron they term the ¡®canopy¡¯ cell. Properties unique to each of the subtypes likely endow them with distinct roles in top-down processing %U https://www.cell.com/trends/neurosciences/fulltext/S0166-2236(19)30001-3