%0 Journal Article %T Myosin II in Cancer Cells Shapes the Immune Microenvironment %J - %D 2019 %R https://doi.org/10.1016/j.molmed.2019.02.011 %X Tumor migration is driven by actomyosin contractility. A recent publication by Georgouli et al. ( Cell 2019;176:757¨C774) describes how crosstalk between the cell migration machinery and tumor-associated macrophages (TAMs) shapes the microenvironment to promote tumor growth. Indirectly targeting TAMs by inhibiting the motility of tumor cells could hinder metastatic spread %U https://www.cell.com/trends/molecular-medicine/fulltext/S1471-4914(19)30048-6