%0 Journal Article
%T Fibroblasts Prompt Tumors to Mobilize Their Glycogen Reserves
%J -
%D 2019
%R https://doi.org/10.1016/j.tcb.2019.02.002
%X Cancer cells use multiple strategies to fuel their unchecked growth. In a recent paper, Curtis et al. ( Cell Metab. 2019;29:141¨C155) delineate a novel strategy whereby cancer-associated fibroblasts (CAFs) secrete cytokines that stimulate glycogen breakdown in ovarian cancer cells. CAF-induced glycogen breakdown increases glycolysis and ATP generation, and facilitates proliferation and metastasis
%U https://www.cell.com/trends/cell-biology/fulltext/S0962-8924(19)30024-8