%0 Journal Article %T The High Energy Cost of Theta¨CGamma Activity during REM Sleep %J - %D 2019 %R https://doi.org/10.1016/j.tins.2019.02.004 %X The occurrence of wake-like electroencephalography (EEG) traces during rapid-eye movement sleep (REM) has intrigued scientists for decades. A recent study by Bergel et al. ( Nat. Commun. 2018;9;5364) imaged brain-wide hemodynamics in rats during wakefulness and sleep. The findings suggest that brain energy expenditure is highest during REM because of heightened theta and gamma activity %U https://www.cell.com/trends/neurosciences/fulltext/S0166-2236(19)30021-9