%0 Journal Article
%T Affordable Preeclampsia Therapeutics
%J -
%D 2019
%R https://doi.org/10.1016/j.tips.2018.12.007
%X Preeclampsia is one of the leading causes of maternal and perinatal morbidity and mortality, particularly in resource-limited settings. Treatment options for this devastating condition remain extremely limited. The successful application of RNAi technology to suppress the pathogenic protein soluble FMS-like tyrosine kinase-1 (sFLT1) in a baboon model of preeclampsia portends the development of effective therapies potentially accessible to areas with the greatest burden of disease
%U https://www.cell.com/trends/pharmacological-sciences/fulltext/S0165-6147(18)30232-3