%0 Journal Article
%T Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor
%J -
%D 2019
%R https://doi.org/10.1016/j.str.2019.02.001
%X £¿ Crystal structure of DOCK7 DHR-2 has been solved in complex with Cdc42 £¿ Structural compatibility accounts for the dual specificity of DOCK7 for Rac and Cdc42 £¿ MD simulations suggest a conformational change of DOCK7 DHR-2 in complex with Rac1 £¿ Structure-based mutagenesis identified specificity determinants of DOCK
%U https://www.cell.com/structure/fulltext/S0969-2126(19)30045-0