%0 Journal Article
%T Structural Basis for the Activation of the Deubiquitinase Calypso by the Polycomb Protein ASX
%J -
%D 2019
%R https://doi.org/10.1016/j.str.2018.11.013
%X £¿ The DmPR-DUB structure reveals molecular details of Calypso interactions with ASX £¿ Ub binding by DmPR-DUB resembles the binding observed in the UCHL5-RPN13-Ub complex £¿ ASX-Ub contacts and stabilization of the crossover loop activate Calypso £¿ Cancer mutations of BAP1 and ASXL1 affect Ub binding and BAP1 activation by ASXL
%U https://www.cell.com/structure/fulltext/S0969-2126(18)30456-8