%0 Journal Article
%T Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by ¦Â-Catenin Mutations
%J -
%D 2019
%R https://doi.org/10.1016/j.cmet.2019.01.002
%X £¿ mTORC1 activation is seen basally in pericentral hepatocytes because of Wnt/¦Â-catenin £¿ CTNNB1-mutated liver tumors are positive for GS and p-mTOR-S2448 £¿ CTNNB1-mutated hepatocellular cancers are addicted to mTORC1 for metabolism £¿ Targeting ¦Â-catenin-GS-mTORC1 axis in liver tumors may enable precision medicin
%U https://www.cell.com/cell-metabolism/fulltext/S1550-4131(19)30002-6