%0 Journal Article
%T Glucose-Regulated TET2 Activity Links Cancer to Diabetes
%J -
%D 2019
%R https://doi.org/10.1016/j.trecan.2018.10.008
%X Diabetes has long been associated with an increased risk of cancer. While many molecular connections likely exist between the diseases, a recent publication discovered a clear molecular link, demonstrating that a glucose-dependent destabilisation of the DNA demethylase TET2 can promote malignant transformation via an AMPK-dependent phosphoswitch
%U https://www.cell.com/trends/cancer/fulltext/S2405-8033(18)30239-5