%0 Journal Article
%T Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events
%J -
%D 2019
%R https://doi.org/10.1016/j.str.2018.11.001
%X £¿ The dynamic assembly shows varying tunnel width, helical rise, and domain orientation £¿ The N-terminal domain and C-terminal tail are not required for CtHsp104 hexamerization £¿ CtHsp104 rescues TDP-43, polyGlu and ¦Á-Syn toxicity in yeast and is well tolerated £¿ CtHsp104 confers thermotolerance to yeast suggesting collaboration with Hsp70/Hsp4
%U https://www.cell.com/structure/fulltext/S0969-2126(18)30420-9