%0 Journal Article
%T Cheating Death: New Molecules Block BAX
%J -
%D 2019
%R https://doi.org/10.1016/j.molmed.2019.02.008
%X BAX is a formidable BCL-2 family protein that executes cellular suicide in response to physiologic and pathologic stress. A new article in Nature Chemical Biology (Garner et al. https://doi.org/10.1038/s41589-018-0223-0) reports small molecules that inhibit the conformational activation of BAX, informing a pharmacologic approach to blocking unwanted cell death in human disease
%U https://www.cell.com/trends/molecular-medicine/fulltext/S1471-4914(19)30043-7