%0 Journal Article
%T Unearthing the Mechanism of Umpolung Amide Synthesis
%J -
%D 2019
%R https://doi.org/10.1016/j.chempr.2019.04.014
%X Umpolung amide synthesis (UmAS) is a new strategy for the construction of amide bonds and is complementary to conventional amide synthesis. However, its mechanistic understanding remains very limited. In this issue of Chem, Johnston and co-workers report the preparation and study of analogs of the tetrahedral intermediates in UmAS
%U https://www.cell.com/chem/fulltext/S2451-9294(19)30172-X