%0 Journal Article
%T Maturation and Clearance of Autophagosomes in Neurons Depends on a Specific Cysteine Protease Isoform, ATG-4.2
%J -
%D 2019
%R https://doi.org/10.1016/j.devcel.2019.02.013
%X £¿ Retrograde transport of autophagic vacuoles requires the motor adaptor UNC-16/JIP3 £¿ Protease ATG-4.2, but not related ATG-4.1, is required for autophagosome maturation £¿ ATG-4.2 cleaves LGG-1/Atg8 to remove it from membranes and enable lysosomal fusion £¿ Transport and maturation mechanisms interact to clear autophagosomes from synapse
%U https://www.cell.com/developmental-cell/fulltext/S1534-5807(19)30104-2