%0 Journal Article
%T Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes
%J -
%D 2019
%R https://doi.org/10.1016/j.stem.2018.10.023
%X £¿ Single-cell RNA-seq stratifies patients with similar clinical presentation £¿ A pseudotemporal profile aligns single cells along a control to disease axis £¿ HDAC4 is mislocalized to the nucleus in PD patient iPSC-derived dopamine neurons £¿ Repurposed compounds correct HDAC4 mislocalization and revert PD-related phenotype
%U https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(18)30504-6