%0 Journal Article
%T The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution
%J -
%D 2019
%R https://doi.org/10.1016/j.devcel.2019.03.001
%X Single-cell gene expression analyses of mammalian tissues have uncovered profound stage-specific molecular regulatory phenomena that have changed the understanding of unique cell types and signaling pathways critical for lineage determination, morphogenesis, and growth. We discuss here the case for a Pediatric Cell Atlas as part of the Human Cell Atlas consortium to provide single-cell profiles and spatial characterization of gene expression across human tissues and organs. Such data will complement adult and developmentally focused HCA projects to provide a rich cytogenomic framework for understanding not only pediatric health and disease but also environmental and genetic impacts across the human lifespan
%U https://www.cell.com/developmental-cell/fulltext/S1534-5807(19)30178-9