%0 Journal Article
%T DNA Damage Signaling-Induced Cancer Cell Reprogramming as a Driver of Tumor Relapse
%J -
%D 2019
%R https://doi.org/10.1016/j.molcel.2019.03.002
%X £¿ DDR signaling induces DNA demethylation at defined loci, including OCT4 and NANOG £¿ macroH2A counterbalances a DDR-signaling-induced activation of OCT4 £¿ MYC and SOX2 cooperate with DDR signaling to activate OCT4 transcription £¿ OCT4 reactivation contributes to cancer drug resistance and tumor relaps
%U https://www.cell.com/molecular-cell/fulltext/S1097-2765(19)30176-5