%0 Journal Article
%T Cut-and-Run: A Distinct Mechanism by which V(D)J Recombination Causes Genome Instability
%J -
%D 2019
%R https://doi.org/10.1016/j.molcel.2019.02.025
%X £¿ A complex between the recombination by-product and RAGs triggers multiple DNA breaks £¿ The breaks co-localize with chromosome breakpoints in acute lymphoblastic leukemias £¿ The breaks occur at many frequently mutated genes in acute lymphoblastic leukemia £¿ Cut-and-run may underpin the most common types of lymphocyte chromosome instabilitie
%U https://www.cell.com/molecular-cell/fulltext/S1097-2765(19)30136-4