%0 Journal Article
%T MST1 Negatively Regulates TNF¦Á-Induced NF-¦ÊB Signaling through Modulating LUBAC Activity
%J -
%D 2019
%R https://doi.org/10.1016/j.molcel.2019.01.022
%X £¿ TNF¦Á induces the recruitment of MST1 to the TNFR1 signaling complex (TNF-RSC) £¿ TRAF2 is required for the TNF¦Á-induced activation of MST1 within the TNF-RSC £¿ MST1 phosphorylates HOIP in TNF-RSC, thereby inhibiting an E3 ligase activity of LUBAC £¿ MST1 attenuates the LUBAC-mediated activation of the NF-¦ÊB pathwa
%U https://www.cell.com/molecular-cell/fulltext/S1097-2765(19)30042-5