%0 Journal Article
%T MDM2 Integrates Cellular Respiration and Apoptotic Signaling through NDUFS1 and the Mitochondrial Network
%J -
%D 2019
%R https://doi.org/10.1016/j.molcel.2019.02.012
%X £¿ Independent of its canonical activities, MDM2 can promote cell death £¿ Cytosolic MDM2 causes oxidative stress, DNA damage, and apoptosis £¿ Cytosolic MDM2 sequesters NDUFS1 to destabilize CI¡¤CIII assembly and enhance ROS £¿ Mitigation of MDM2-induced mitochondrial ROS prevents DNA damage and subsequent apoptosi
%U https://www.cell.com/molecular-cell/fulltext/S1097-2765(19)30102-9