%0 Journal Article
%T Crossing the Mucosal Barrier: A Commensal Bacterium Gives Dengue Virus a Leg-Up in the Mosquito Midgut
%J -
%D 2019
%R https://doi.org/10.1016/j.chom.2018.12.009
%X Commensal bacteria that colonize the midgut of Aedes aegypti mosquitoes can influence the transmission of arthropod-borne viruses. In this issue of Cell Host & Microbe, Wu et al. (2019) Wu P. Sun P. Nie K. Zhu Y. Shi M. Xiao X. Liu H. Liu Q. Zhao T. Chen X. et al. A gut commensal bacterium promotes mosquito permissiveness to arboviruses. Cell Host Microbe. 2019; 25 ( this issue) : 101-112 Google Scholar show that Serratia marcescens bacteria secrete enhancin proteins that cleave membrane-bound mucins, thereby facilitating dengue virus infection of midgut epithelial cells
%U https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(18)30636-X