%0 Journal Article
%T Induction of Selenoprotein P mRNA during Hepatitis C Virus Infection Inhibits RIG-I-Mediated Antiviral Immunity
%J -
%D 2019
%R https://doi.org/10.1016/j.chom.2019.02.015
%X £¿ SeP, a hepatokine causing insulin resistance, is increased in HCV patients £¿ SeP mRNA binds to RIG-I and inhibits RIG-I-mediated type I IFN immune responses £¿ The full-length structure of SEPP1 mRNA is required to regulate RIG-I activity £¿ Increased serum SeP in chronic hepatitis C patients is associated with DAAs failur
%U https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(19)30111-8