%0 Journal Article
%T Centriole Biogenesis: Symmetry Breaking and Site Selection
%J -
%D 2019
%R https://doi.org/10.1016/j.tcb.2018.11.001
%X Centrioles must duplicate as cells progress through the cell cycle but it is unclear how the site of duplication is selected. A recent computational study demonstrates that two separate but interacting feedback mechanisms (autocatalytic activation and substrate depletion) are capable of selecting a single site for centriole biogenesis
%U https://www.cell.com/trends/cell-biology/fulltext/S0962-8924(18)30187-9