%0 Journal Article
%T Heterogeneity Studies of Mammalian Cells for Bioproduction: From Tools to Application
%J -
%D 2019
%R https://doi.org/10.1016/j.tibtech.2018.11.007
%X Current bioprocess analytics (cell growth, productivity, metabolic rates, etc.) result in average values neglecting the suspected ¨C and in many cases known ¨C heterogeneity within isogenic cultures. This heterogeneity may lead to subpopulations becoming dominant and being responsible for process variability, reduced reproducibility or even process failure
%U https://www.cell.com/trends/biotechnology/fulltext/S0167-7799(18)30317-2