%0 Journal Article %T Combined Single-Cell Profiling of lncRNAs and Functional Screening Reveals that H19 Is Pivotal for Embryonic Hematopoietic Stem Cell Development %J - %D 2019 %R https://doi.org/10.1016/j.stem.2018.11.023 %X £¿ Single-cell transcriptome profiling constructs lncRNA landscape of HSC development £¿ Computational and functional screening identifies 6 lncRNAs affecting hematopoiesis £¿ Loss of H19 lncRNA results in failed HSC generation from endothelium in AGM region £¿ H19 deficiency leads to promoter hypermethylation of Runx1 and Spi1 in pre-HSC %U https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(18)30559-9