%0 Journal Article
%T Formylation of Eukaryotic Cytoplasmic Proteins: Linking Stress to Degradation
%J -
%D 2019
%R https://doi.org/10.1016/j.tibs.2018.12.008
%X Unlike prokaryotes, N-terminal formylation has been confined to a handful of mitochondrial proteins in eukaryotes. A recent study unveils a new role for eukaryotic cytoplasmic N-terminal formylation linking diverse cellular stresses to N-terminal-dependent protein degradation. These findings suggest broad cellular implications in higher eukaryotes for N-terminal methionine formylation
%U https://www.cell.com/trends/biochemical-sciences/fulltext/S0968-0004(18)30274-3