%0 Journal Article %T The Limited Information Capacity of Cross-Reactive Sensors Drives the Evolutionary Expansion of Signaling %J - %D 2019 %R https://doi.org/10.1016/j.cels.2018.12.006 %X £¿ Cooperativity or allostery do not increase the signaling capacity £¿ Copy number variation and cross-reactivity severely restrict signaling capacity £¿ Duplication of cross-reactive receptors doubles capacity even with minimal divergence £¿ Duplication with minimal divergence yields multiple cross-wired signaling pathway %U https://www.cell.com/cell-systems/fulltext/S2405-4712(18)30480-0