%0 Journal Article
%T Recurrent Loss-of-Function Mutations Reveal Costs to OAS1 Antiviral Activity in Primates
%J -
%D 2019
%R https://doi.org/10.1016/j.chom.2019.01.001
%X £¿ Co-expression of primate OAS1/RNase L in yeast reveals functional diversity £¿ Common polymorphisms in human and gorilla OAS1 encode reduced 2¨C5A production £¿ Low-activity OAS1 alleles are pervasive in Old and New World monkeys £¿ OAS1 enzymatic activity appears completely lost among species of tamarin monkey
%U https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(19)30038-1