%0 Journal Article
%T Non-syndromic Mitral Valve Dysplasia Mutation Changes the Force Resilience and Interaction of Human Filamin A
%J -
%D 2019
%R https://doi.org/10.1016/j.str.2018.09.007
%X £¿ FLNA-MVD-causing mutation only slightly changes the FLNa structure £¿ SMD simulations suggests that in FLNA-MVD cellular force transmission is altered £¿ The main binding site for PTPN12 in FLNa is in domain FLNa4 £¿ FLNA-MVD-causing mutation interferes the binding of the PTPN1
%U https://www.cell.com/structure/fulltext/S0969-2126(18)30333-2