%0 Journal Article
%T The Septate Junction Protein Tsp2A Restricts Intestinal Stem Cell Activity via Endocytic Regulation of aPKC and Hippo Signaling
%J -
%D 2019
%R https://doi.org/10.1016/j.celrep.2018.12.079
%X £¿ The assembly of septate junctions (SJs) occurs during ISC-EC differentiation £¿ The SJ protein Tsp2A undergoes internalization and mediates aPKC degradation £¿ Normal Tsp2A-SJ assembly ensures Hippo signaling to restrict ISC proliferation £¿ Defective Tsp2A-SJ assembly causes aPKC accumulation and Yki hyperactivit
%U https://www.cell.com/cell-reports/fulltext/S2211-1247(18)32024-2