%0 Journal Article %T Efficient Single-Strand Break Repair Requires Binding to Both Poly(ADP-Ribose) and DNA by the Central BRCT Domain of XRCC1 %J - %D 2019 %R https://doi.org/10.1016/j.celrep.2018.12.082 %X £¿ Interaction of XRCC1 with PAR and DNA are both mediated by the central BRCT domain £¿ Interaction with PAR and DNA occurs through non-overlapping binding surfaces £¿ Mutational disruption of DNA binding to XRCC1 impairs recruitment to DNA damage £¿ Disruption of DNA binding by XRCC1 impairs repair of DNA single-strand break %U https://www.cell.com/cell-reports/fulltext/S2211-1247(18)32042-4