%0 Journal Article
%T Modeling the Pathological Long-Range Regulatory Effects of Human Structural Variation with Patient-Specific hiPSCs
%J -
%D 2019
%R https://doi.org/10.1016/j.stem.2019.03.004
%X £¿ Disrupting the TFAP2A regulatory domain causes branchiooculofacial syndrome (BOFS) £¿ Enhancer disconnection leads to monoallelic and reduced TFAP2A expression £¿ Placing enhancers and genes within a TAD is not sufficient for enhancer adoption £¿ Patient-specific hiPSC-derived neural crest to uncover long-range pathomechanism
%U https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(19)30103-1