%0 Journal Article
%T Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding
%J -
%D 2019
%R https://doi.org/10.1016/j.str.2019.01.015
%X £¿ We solved the crystal structure of hAsh1L bound to Mrg15 £¿ hAsh1L interacts with Mrg15 mainly via an N-terminal extension £¿ The autoinhibitory loop of hAsh1L is disordered upon Mrg15 binding £¿ Mrg15 binding induces displacement of SA
%U https://www.cell.com/structure/fulltext/S0969-2126(19)30015-2